About the Author
Written by Kelsey Costa, MS, RDN on October 2, 2024
Fact checked by Jill Seladi-Schulman, Ph.D.
Cafestol: Exploring Its Potential Benefits for Metabolic Health
Cafestol, a natural diterpene compound found in unfiltered coffee, has been linked to various aspects of metabolic health. Recent research suggests that a dosage of 6 milligrams of cafestol taken twice daily for 12 weeks may lead to modest reductions in weight and body fat, although it does not appear to enhance insulin sensitivity or glucose tolerance.
Understanding Cafestol
Cafestol is prevalent in coffee brewed through unfiltered methods, such as French press, Turkish, and espresso. Beyond its contribution to coffee’s flavor and aroma, cafestol may hold potential health benefits. Danish researchers have investigated its effects on insulin sensitivity and metabolic markers, suggesting it could help in preventing type 2 diabetes.
Recent Study Findings
In a recent randomized controlled trial published in Nutrients, researchers aimed to evaluate the effects of pure cafestol on metabolic health among healthy individuals with high waist circumferences—a known risk factor for diabetes. The study involved 40 adults aged 25 to 78 who were not diagnosed with diabetes or significant health conditions.
Participants were divided into two groups: one received cafestol capsules, while the other received a placebo. Throughout the study, participants were allowed unlimited amounts of paper-filtered coffee, which contains negligible cafestol, but were limited to one unfiltered coffee per day.
After 12 weeks, results showed that while cafestol did not improve insulin sensitivity or glucose tolerance, it was associated with a reduction in body weight and visceral fat. Specifically, those taking cafestol lost an average of 880 grams, while the placebo group gained 920 grams. The cafestol group also demonstrated a reduction in a liver enzyme, gamma-glutamyl transferase.
Implications for Metabolic Health
Despite the study’s limitations, the findings contribute valuable insights into the relationship between coffee consumption and diabetes risk. While cafestol may aid in weight loss, concerns arise regarding its potential to increase insulin resistance, which could counteract its benefits.
Experts suggest that cafestol might enhance fat metabolism, thereby supporting weight loss and reducing visceral fat. However, further research is needed to clarify its role in metabolic health and diabetes prevention.
Recommendations for Coffee Consumption
While the study’s findings are intriguing, they do not provide conclusive evidence for using coffee as a diabetes prevention strategy. Moderate coffee consumption—about 2 to 3 cups per day—has been associated with cardiovascular and metabolic health benefits. For those interested in maximizing coffee’s health advantages, experts recommend:
- Opting for organic and unfiltered coffee (like French press) to retain beneficial compounds.
- Avoiding added sugars and high-fat creamers to enhance potential benefits.
- Drinking coffee earlier in the day to prevent sleep disturbances.
- Grinding coffee beans at home for freshness and higher nutrient content.
Conclusion
Cafestol shows promise in supporting weight management and metabolic health, but more comprehensive studies are needed to understand its full impact. Those considering incorporating unfiltered coffee into their diet should do so in moderation and be mindful of overall dietary patterns.
